Bariatric Surgery vs. GLP-1 Medications: What the Latest Research Shows

New Study Highlights Superiority of Bariatric Surgery Over GLP-1 Medications for Sustained Weight Loss

A new real-world study presented at the ASMBS 2025 Annual Meeting compares outcomes between GLP-1 medications (such as semaglutide and tirzepatide) and bariatric surgery. The findings show that patients who underwent sleeve gastrectomy or gastric bypass lost approximately five times more weight over two years than those taking GLP-1 medications.

While GLP-1 drugs continue to play a role in obesity treatment, this study reinforces that bariatric surgery remains the most effective and durable option for significant, long-term weight loss.
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